Detour - Edgar G. Ulmer (1945)

Film noir thriller, and cult movie they say."It could happen to you" kind of story with an efficient voice-over being wise. A virtuous pianist goes west hitchhiking (so his art wasn't decently paid) and chance takes care. Then a "Cigarette-puffing femme fatale" (Ann Savage, what a name) tries to handle him without care.